Leptin(LEP) is a hormone created by fat cells that regulates the number
of fat stored in the body. Leptin is secreted and circulates through
the body, eventually activating leptin receptors in the bowed nucleus of
the neural structure. Energy expenditure is accumulated each by the
signal to the brain, and directly via leptin receptors on peripheral
targets.
Although regulation of fat stores is deemed to be the first perform of leptin, it additionally plays a role in alternative physiological processes, as proved by its multiple sites of synthesis alternative in than fat cells, and also the multiple cell sorts beside neural structure cells that have leptin receptors. Several of those extra functions are however to be outlined. Leptin circulates in blood in free morpheme and absolute to proteins. Leptin levels vary exponentially, not linearly, with fat mass. Leptin levels in blood are higher between hour and early morning, maybe suppressing appetency throughout the night. The diurnal rhythm of blood leptin levels can be changed by meal-timing.
The LEP ELISA Kit( www.cusabio.com/html/product/CSB-E04649h.html ) is a 3.5 hour solid phase ELISA designed to measure soluble human Leptin in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human Leptin and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Leptin accurately.
Although regulation of fat stores is deemed to be the first perform of leptin, it additionally plays a role in alternative physiological processes, as proved by its multiple sites of synthesis alternative in than fat cells, and also the multiple cell sorts beside neural structure cells that have leptin receptors. Several of those extra functions are however to be outlined. Leptin circulates in blood in free morpheme and absolute to proteins. Leptin levels vary exponentially, not linearly, with fat mass. Leptin levels in blood are higher between hour and early morning, maybe suppressing appetency throughout the night. The diurnal rhythm of blood leptin levels can be changed by meal-timing.
The LEP ELISA Kit( www.cusabio.com/html/product/CSB-E04649h.html ) is a 3.5 hour solid phase ELISA designed to measure soluble human Leptin in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human Leptin and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Leptin accurately.
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