2014年7月21日星期一

An ultrastructural investigation of dermatopontin

Dermatopontin is an extracellular matrix protein with functions in cell-matrix interactions and matrix assembly. Dermatopontin is found in numerous tissues. Dermatopontin is postulated to switch the behavior of TGF beta through interaction with decorin. Dermatopontin is a cosmopolitan small relative molecular mass protein in the extracellular matrix and its homologues in 5 mammals and several other invertebrates. The structures of those homologues are comparatively well preserved among the species. In the skin, dermatopontin is found in the surface of the albuminoid fibers. It's found in the conditioned medium and in the living substance of civilised fibroblasts. Early studies targeted on electronic countermeasures assembly and interactions.
The expression of dermatopontin around an infarction zone of experimental infarction might support this chance. In invertebrates, dermatopontin homologues act primarily as agglutination molecules. We have a tendency to found that reworking growth factor-beta1 interacts with dermatopontin and the operate of this protein is changed by dermatopontin. In order to obtain an accurate diagnostic data in biological experiments. Biologists will use a dermatopontin ELISA kit. The dermatopontin ELISA kit( www.cusabio.com/ELISA_Kit-75282/ ) has been pre-coated with an antibody specific to DPT. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. The OD value is proportional to the concentration of DPT. We can calculate the concentration of DPT in the samples by comparing the OD of the samples to the standard curve.

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