2015年6月12日星期五

Immune cells reveal "secret agent 007" is the manufacturing process


   Recently, an article published in the international journal Nature Immunology research papers, there are scientists who study reveals the immune cells by "spy 007" is manufactured in the process, or to clarify how the immune system protects the body against disease provide some help.

   Dendritic cells are a rich source of wisdom immune cells, which can gather a lot of information on viruses, bacteria, fungi, cancer and to help the immune system resist disease invasion, and understand how they are manufactured to generate dendritic cells may help scientists develop new ways to enhance the body's immune response against infection. Scientists say that dendritic cells can "educate" the immune system, it will tell against infected T cells and NK cells viruses, bacteria, fungi or cancer looks like, so that these cells can be targeted to kill the intruders.

   If we learn how to control dendritic cells, then we might enhance their immune response against infection, or autoimmune diseases decreased damage to the body. For this study, researchers used the latest technology to detect a single immune cells and their progeny, and found that for all subsets of dendritic cells and not in terms of their so-called single progeny, but for each but there are subtypes of cells only special progenitor cells. Targeting progenitor cells may help develop new therapies against a variety of infections, a progenitor cell can be made to produce a plurality of daughter cells, and progenitor cells to produce a variety of inhibiting dendritic cell subsets may sometimes be effective in treating a variety of self-help immune diseases. Similarly, special dendritic cells induce additional generation might improve the immune response of the body to resist infection or a vaccine.

   Finally, the researchers say, the evolutionary family tree draws blood cells may help understand the mechanisms of disease, and the body of each of the blood and immune cells are made of blood stem cells from the differentiation and development. So tracking evolutionary tree can be found starting each type cells, but also can explain how parental cell determines the direction of the next step of development. By analyzing the genetic characteristics of different cells, researchers can look for to treat a range of infectious diseases, cancer and immune disorders and other diseases of the new targets.
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