Methods for the treatment of "iron overload" syndrome

　　A form of the hereditary disease is inherited blood disease.Not everyone who would have inherited genes have to the disease, but those who do, gene from both parents genetic defects.Inherited blood disease is in the northern europeans find the most common people.
　　Over the past few years, those with diseases will see too much iron in the liver, heart, pancreas, joint and the pituitary gland, lead to health problems, such as liver cirrhosis, liver cancer, diabetes, heart disease and joint disease.And disease can get their blood routine to get rid of the excess iron.
　　"Over the past 150 years, we don't know how iron has been adopted by the liver - how to get there," Mitchell Knudsen, associate professor of food science and human nutrition ufida said."We know there is put it into a protein to the liver. However, no one knows what the protein, it is such a fundamental problem, people just don't know the answer."
　　Scientists now know, this is ZIP14 protein.
　　Published online in the journal of the cell metabolism, a new study on 28th knutson and his colleagues found that mice lacking ZIP14 - when mating with mice blood disease - no load of iron in the liver.
　　As the new found that scientists can design drugs targeted ZIP14 prevent iron from loading in the liver.Such drugs, however, will need to use a combination of combination of drugs and to remove iron from the body currently, knutson described below.
　　Although scientists found that the progress of the hemochromatosis, not disorderly already has a relatively simple process: bloodletting.But Knudsen do see the findings as more relevant iron overload may treat other difficult and complicated diseases, such as the Mediterranean anemia.The Mediterranean anemia patients cannot make healthy red blood cells, so need regular blood transfusion to maintain life.

　　Blood transfusion is introduced into the large amounts of iron in the blood, thus rapidly to the liver.If can prevent liver iron load - through methods such as blocking ZIP14 - it will be easier to get in the extra iron in the blood drug from the body.
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