Researchers in Japan have found through recombinant human proteins that after retinitis pigmentosa degeneration in mice transplanted by the induction of pluripotent stem cells (iPS cells) cultured cells, some mice restored the ability to perceive light. The results bring new hope of light for the retinal pigmented patients.
Retinitis pigmentosa is a hereditary disease. The retina which can respond to light in the visual cells gradually disappear, resulting in vision degradation and severely blindness. There is no effective cure.
Japan's Institute of Physical and Chemical Research said a research team at the Institute of Multi-Cell System Research Center using experimental mouse iPS cell cultured and obtained visual cells and transplanted to the eyes of mice suffering from retinitis pigmentosa blindness.
Researchers conducted electric shock to test visual recovery in mice through light. In the experiment, the mice were exposed to light for 5 seconds without electric shock. The results showed that about 40% of the mice receiving single-eye transplantation responded to light and avoided electrical shock, while those not receiving transplantation did not avoid electric shock.
According to the researchers, the visual cells they transplanted to mice were less than 5% of all cells. If transplanted a larger range of visual cells to retinal, the ratio of mice restoring vision may be higher.
The relevant papers have been published in the online edition of the journal Stem Cell Report in United States. The researchers plan to apply for human clinical trials within two years further on the basis of confirmation of safety. Flarebio provides you with superior recombinant proteins like recombinant COLEC12 at good prices.
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