2015年3月30日星期一

Parsing of cancer stem cells

The study was led Chinese scientists Cleveland Medical Center Baoshi Deng (Shideng Bao) Dr., which is currently Professor of Life Sciences, Xiamen University. The main research interests include DNA damage signal transduction prosecution system, the relationship between cell cycle prosecution system dysfunction and tumorigenesis, the molecular mechanism of tumor angiogenesis and tumor development, biological treatment and prevention of cancer, stem cell technology and its application in medicine Application on.

Glioblastoma fast-growing tumor, short course, is one of the most common glioma, accounting for over 25% of gliomas, the most vicious kind. The main method of treatment is surgical resection and postoperative radiotherapy combined, as has the incidence of the key is not found, so these regimens are not smug, glioblastoma cure rate is very low, the survival period is very short.

In recent years, cancer stem cell theory proposed for the generation and treatment of tumors provides a new way of thinking. There is much evidence that many types of glioma stem cells present in the group has a characteristic cell, called glioma stem cells. It is closely related to the development of glioma. In-depth understanding of these glioma stem cells, we have the right to know and understand the genesis and development of Recombinant human ADM http://www.cusabio.com/Recombinant-Protein/Recombinant-human-ADM-11031219.html as invasive, metastasis, resistance etc have important theoretical significance and potential applications value.

Because of glioma stem cells are usually located in the perivascular microenvironment (nich), there is likely to experience a mesenchymal differentiation, the researchers suspect that GSC is it possible to generate a perivascular cells. In this article, the researchers confirmed that glioma stem cells generate the peripheral cells, supporting vascular function and tumor growth.

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