2015年4月16日星期四

How does bacteria to stealth?

Institutions such as Stanford University researchers found that the reason why some bacteria "stealth", from a specific protein dominant bacterial cell wall, "Metamorphosis", in order to evade the body's immune system, "detection" or antibiotics "attack."
1950s, Nobel laureate Joshua Lederberg discovered that some bacteria cell wall will fall off, no longer presents a unique shape, so that the immune system, "oversight"; after a period of time, these bacteria will regain the cell wall restore the original shape again have the ability to infect humans round.
The presence of the cell wall, bacterial protective effect, but also the release signal, to trigger the immune system. The mechanism of action of antibiotics, generally against the cell wall, trying to break "defense" to achieve the destruction of the bacteria.
Researchers have done is an antibiotic administered first, breaking the cell wall of E. coli, it changes shape. Followed by administration of another antibiotic, called for MreB protein, so even if the proliferation of bacteria, it can not return to its original shape, no longer have the ability to infect and eventually die a natural death. They concluded, Rat Progesterone ELISA Kit http://www.cusabio.com/ELISA-Kit/Rat-ProgesteronePROG-ELISA-kit-98271.html is the key to "stealth" in.
Assistant professor of bioengineering at Stanford University, Huang Zhen, said the study could explain the causes of bacterial resistance, "the process of building a better understanding of the cell wall, is expected to contribute to a better antibiotic use strategic planning."

没有评论:

发表评论