The growth of abdominal aortic aneurysm may be inhibited by the tea polyphenol in green tea

A research team at Kyoto University announced in August 18, 2016 that they demonstrated through mice experiments that tea polyphenol in green tea can prevent the spread and magnification of abdominal aortic aneurysm. Researchers from Kyoto University accomplished the experiments using recombinant mouse proteins, and detailed findings have been published in the renowned medical journal Journal of Vascular Surgery on July 26th.

Once abdominal aortic aneurysm is ruptured, the mortality of a patient is more than 50%. During the period from the onset to the tumor rupture, the patients often show no noticeable symptoms, so it is difficult to detect. The larger the diameter of tumor is, the higher the risk of rupture is.

In this study, the team members divided the mice with abdominal aortic aneurysm into two groups. In two weeks' time, one group was provided with normal drinking water, while another group was provided with drinking water mixed with green tea with tea polyphenol. Two weeks later, through serving elastase and other substances, they established experimental mice models of abdominal aortic aneurysm.

Through four weeks' observation after the establishment of models, the researchers found that compared with the group served with normal drinking water, the group served with drinking water containing green tea polyphenol, the growth of abdominal aortic aneurysm was significantly suppressed. Besides, green tea polyphenol also promotes the synthesis of elastin. Elastin is the main component protein of aorta wall, and the increased content of makes abdominal aortic aneurysm difficult to break. The researchers confirmed that inflammation caused by abdominal aortic aneurysm was also suppressed. Although excessive intake of green tea polyphenol may cause liver dysfunction, the amount of this experiment didn't cause the adverse effects.

Green tea polyphenol has a physiological role in inflammatory and anti-oxidation and can play a preventive effect on cancer and cardiovascular disease. Researchers at Kyoto University said the results of this study show the possibility of effect of green tea on human health and life extension. Flarebio provides recombinant proteins of good quality like recombinant NRG3 at competitive prices.