Australian National University announced on 10th that researchers of the school have new findings of a group of proteins which helps to turn on or off some gene expression in the blood cell generation process, which helps to develop new and more effective breast cancer drugs.
Through a lot of studies using recombinant proteins such as recombinant horse proteins, researchers reveal the working mechanism of a group of specific proteins - chromatin helicase DNA binding protein (CHD). The group of proteins consists of the nucleosome remodeling deacetylase. This enzyme can turn on or off certain gene expression in the replication process of blood cells and stem cells. One of the proteins, CHD4, is associated with breast cancer, while there are no drugs specifically for this protein among existing drugs to treat breast cancer.
Dr. Daniel Ryan from Medical Research Centre of John Curtin at the Australian National University said that some currently-used breast cancer treatments are effective, but their mechanisms are not clear. While the research he is undertaking reveals the working mechanism of CHD4, which would make it possible to specifically develop super drugs of this protein for the treatment of breast cancer later. More precisely targeted therapies will reduce the toxicity of the drug and reduce resistance.
He said the researchers still need to break down this enzyme in order to explore how different proteins work with each other and to learn how complex molecular structures operate. Flarebio Biotech LLC is a National High-Tech Enterprise with research, production and sales as one. It provides you with superior recombinant proteins like recombinant ITGB2 at good prices.
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