2015年12月6日星期日

cTnI, a biochemical index for early prognosis of patients with unstable angina pectoris

A new research is conducted recently to evaluate the early prognostic value of quantitative detection of cardiac troponin in patients with unstable angina pectoris. 88 cases of patients with unstable angina pectoris in the onservation group and 54 cases of healthy people in the control group were tested serum cTnl and creatine kinase (CK-MB) and the incidence og cardiac events in the observation group was observed.

The results are as follow: the average quantitative determination of cTnl was (0.34±0.02) ng/mL in the observation group, that of te control group was (0.01±0.00) ng/mL and the difference between the two groups was statistically significant (P <0.05); the difference of CK-MB levels in the two groups was not staistically significant. Among the 88 cases of patients, 35 cascs were detected positive for scrllm cTnl (cTnl≥0.1 ng/mL), 53 cases were detected negative for serum cTnl (cTnl<0.1 ng/mL). The incidence iof acute myocardial infarction, cardiac death and inteactable angina during hospitalization was 82.9% in the patients with cTnl positive, the incidence foe the patients with Ctnl negative was 18.9% and the difference was stastically significant (P<0.01).

In conclusion, cTnl is a biochemical index reflecting high sensitivity and specificity of myocardial cell injury and the quantitative determination of cTnl has a good predictive value for early prognosis of patients with unstable angina pectoris.

Read more: http://www.cusabio.com/Polyclonal-Antibody/Rabbit-anti-human-Transcription-factor-p65-polyclonal-Antibody-11106202.html

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