To locate and surveil immune cell of human body with new technology

The immunotherapy of using human immune cells to attack cancer cells is the current international scientific research focus, but how immune cells specifically functions in vivo has always been a mystery. US researchers have recently developed a new method for the first time through recombinant rat proteins to achieve location and surveillance of immune cell of human body.

At this stage, immunotherapy still has its limitations. The effect of immune cells finding and killing cancer cells is sometimes better than conventional cancer therapy, but sometimes does not work. Doctors often have to wait a few months to check whether the tumor shrinks to know whether the immune cells attack cancer cells. If immunotherapy does not work, then the cancer cells may have spread or become more difficult to deal with.

Researchers at Stanford University and other researchers in the United States reported online on the academic journal Science Translational Medicine that they have spent 10 years and have found a way to track immune cells.

They have genetically engineered immune cells from patients and added a "reporter gene", a gene that directs the synthesis of a protein that can be detected by positron emission tomography. After the genetically-modified immune cells being injected back to the human body, by detecting the relevant protein, we can know the location of immune cells, the number of information, and we can analyse whether they are close to the tumor and attack.

The researchers successfully tested this technique in glioblastoma patients. They say that new technologies can also be used to track immune cells against other cancers. "The technique, which can show how the living body's immune system works without removing any human tissue, is unprecedented," says research director, Professor Sanjee Gambier from Stanford University. Flarebio offers superior recombinant proteins such as recombinant Dpp4 at good prices.