Preoperative supplement VD reduce the risk of thyroid cancer

According to the latest study of 2014 meeting of the American Thyroid Association (ATA), preoperative vitamin D deficiency significantly increased the risk of thyroid cancer patients rows total thyroidectomy and central compartment neck dissection (CCND) postoperative hypocalcemia before surgery is recommended for oral vitamin D, so that preoperative vitamin D deficiency in thyroid cancer patients were symptomatic hypocalcemia risk minimization.

Although vitamin D deficiency had been with Graves' disease and toxic multi-nodular goiter patients with total thyroidectomy postoperative hypocalcemia related, but its role in patients with thyroid cancer is unclear.

Korea Severance Hospital, Kee-Hyun Nam, MD, led the research team of 267 cases underwent total thyroidectomy and thyroid cancer CCND conducted a survey in which 73 cases defined as preoperative vitamin D deficiency (Mouse TNFRSF1B ELISA Kit http://www.cusabio.com/cusabio-109389/), the remaining 194 cases of normal (vitamin D levels ≥10ng / ml).

Postoperative incidence of symptomatic hypocalcemia, vitamin D deficiency preoperative patient group than in the control group (43.8% vs 30.4%, P = 0.043). According to the demand for intravenous infusion of calcium, low postoperative serum parathyroid hormone levels (<15pg / ml) was the strongest predictor of hypocalcemia (P <0.001). But a predictor of preoperative vitamin D deficiency is symptomatic hypocalcemia (P <0.007), the odds ratio was 3.00.

Postoperative patients with low thyroid hormone levels, and if they are also vitamin D deficiency, will show a significantly higher proportion of symptomatic hypocalcemia (77.5% vs 53.2% of non-deficient group, P = 0.008).