2014年11月4日星期二

Scientists unlock mystery of cell division is important

Cell division process is essential for life. Since the emergence of the Victorian era of cell biology, the final stage of cell division - the two daughter cells separated from each other in the process has been so fascinated scientists. However, in the past a very long time, to study the final step before the process of cell division that is divided into two furrow formation is extremely difficult.

Early biologists will be named this process "cytokinesis" , has been interpreted as a "cell movement" and a series of highly active and organized events. Scientists now have more understanding of proteins and their associated behavior, but there is an important puzzle remains unsolved: how cells send signals to the cleavage furrow at?

A simple reason for this lies in the blind spot: is difficult to see and detect such complex processes in living cells. Now, the system biologist at Harvard Medical School in the "Science" magazine reported that they rebuilt cytokinesis in cell-free conditions - including some of the molecular signals directing traffic. Combined with frog egg extracts and analog cell membrane lipid membrane, they constructed a cell-free system repeat furrow assembly process. Cusbaio offer SHEEP INS ELISA KIT http://www.cusabio.com/ELISA_Kit-84822/ for use in common research applications. Each SHEEP INS ELISA KIT is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it.

The cell-free system has two great advantages: it expands the size of the event furrow constructed so that they become easier to observe, and to provide a simple study of the method for manipulation of related proteins. When the cells intact, it is difficult to achieve rapid removal and restoration of certain proteins were observed to change the role of the molecule for cytokinesis effect, and when the internal structure of the cells spread on a microscope slide of it becomes very easy .

The key challenge lies in cytokinesis behavior is totally dependent on the cell membrane to form a cleavage furrow - and build the cell membrane of the cell-free system must be removed. Recognizing the flat membrane can be controlled using a glass composed of two layers of lipids manually, instead of bending, the complex membrane constantly moving, making it possible to work in this study.

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