2014年12月9日星期二

The driving mechanism of the body's uptake of glucose in the brain

Glucose is a carbohydrate component, which is also the main source of energy used by brain cells, recently, researchers from Imperial College London studied by rat identified a novel mechanism that reveals into the brain glucose content, and the ability to stimulate the brain in animals actively looking glucose absence of glucose, research published in the international Journal on JouRNAl of Clinical Investigation.

The researchers believe that this mechanism plays in favor of human-driven sugar and starchy foods in an important role, said Dr. James Gardiner, our brains rely on large amounts of glucose for energy, while glucose is an important nutrient, but in the past evolutionary process, we are difficult to obtain glucose, so we have to glucose-rich foods like deep-rooted feelings and preferences of Mouse hepatitis B virus e antigen ELISA Kit http://www.cusabio.com/ELISA_Kit-82185/ .

Article, the researchers assume that enzymes called glucokinase glucose in driving our "enthusiasm" on plays an important role, glucokinase can participate in the liver and pancreas to glucose sensing process, and the presence of glucokinase in the hippocampus, may be necessary to regulate the body's various functions, including food intake, but the specific molecular mechanism involved is not yet clear. The researcher found that when rats 24 hours without eating, the brain hippocampus appetite regulation center glucose kinase activity will be significantly increased.

When the researchers used a virus to increase the hippocampus glucokinase activity, they found that rats will give priority to food consume more glucose, and when the glucokinase activity decreased, the amount of glucose consumption would be reduced accordingly . Said Dr. Gardiner, in this study we first found in the brain of the existence of such a special nutrient reaction system, it is not just energy intake system, when we recall the time of their daily diet would think different nutrients, rather than heat.

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