2017年3月1日星期三

Autism-related gene variations improve brain evolution

Researchers at Yale University in the United States published a paper in the journal Public Library of Genetics that the genetic variation associated with autism may be a positive choice in the evolutionary process because these variations also help to increase human cognitive ability. More research through recombinant mouse proteins should be conducted.

In the long evolutionary process, humans produce a lot of genetic variation, and the effects of these variations on human genetic characteristics are positive and negative. Those who have a negative impact on human reproduction will be eliminated in the evolutionary process; and if the emergence of mutations can improve the chance of human survival, it will become a positive choice of human beings and be retained in the genome and be passed down generation by generation.

In this study, the researchers conducted a genome-wide association study of more than 5,000 cases of autism, and they analyzed the gene selection in human evolution. They found that genetic variation associated with autism is more of a positive choice in human evolutionary processes that are not only related to autism but also to human intelligence. For example, many autistic-related gene mutations identified by the researchers can enhance brain cell function and help to create new neurons.

Researchers point out that genetic variation that increases the risk of autism is a positive choice in the evolution of humans. This may make people feel unimaginable: why do a large number of autistic pathogenic gene mutations remain in the human genome? Why don't humans eliminate them in the evolutionary process? The reason is that these variations have a positive effect on human cognitive function, so it is actively chosen in the evolutionary process, and the cost is an increase in the risk of autism. Flarebio provides you with high-quality recombinant proteins like recombinant PIGR at good prices.

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