2017年3月6日星期一

Researchers have found the key to molecular aging in the blood and immune systems

The team at the new University of California, San Francisco has found the key to molecular aging in the blood and immune systems, and it is expected to address chronic diseases, anemia, blood cancer and various diseases caused by infection. The study has been published in the journal Nature, which also publishes other studies on recombinant rat proteins.

The researchers said, "In addition to the normal cell waste disposal, the autophagy has influences on the orderly maintenance of hematopoietic stem cells (hsc), as well as the whole immune system resist to infection and treatment of pathogens.

The researchers found that autophagy can inhibit hepatic stellate cells so that the hepatic stellate cells with active metabolism can come back to resting and quiet state. This is a new discovery of autophagy in stem cell organisms. Inactivated autophagy has a profound effect on the blood system, leading to imbalance in some types of white blood cells. Autophagy also reduces the ability of hepatic stellate cells to regenerate.

By testing in mice, the researchers found that 70% of spleen cells in aging mice did not develop autophagy and showed a dysfunction. In addition, scientists have found many different tissue stem cells, and all the performance will be reduced with age.

"This finding provides a new perspective for anti-aging, focusing on the old hepatic stellate cells and slowing down the aging blood system. And we want to find a real ability to improve stem cells themselves and use this ability to help older people and provide them with a better immune system to resist infection by preventing the development of blood diseases. Flarebio provides recombinant proteins of good quality such as recombinant Itgb5 at reasonable prices.

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