2017年3月27日星期一

To produce new proteins to achieve a variety of magical functions

Protein structure almost has unlimited possibilities. According to our needs to design and manufacture of proteins, it is possible to achieve a variety of magical functions through a lot of recombinant mouse proteins.

Protein is the "labor" of all living creatures, carrying out various orders from DNA. It also has a variety of complex structures to achieve all the important functions of humans and all organisms, including digestive food, tissue growth, blood oxygen transmission, cell division, neuronal activation, muscle supply and so on. Surprisingly, the function of such a diversity of proteins comes only from the combined sequence of 20 amino acid molecules in the region. Until now, the researchers have just begun to understand how these linetypes are folded into complex structures.

Even more surprising is that nature seems to use only a small part of all possible protein structures, although the latter is large in number. Therefore, the use of existing amino acid design with a special structure of the unconventional protein, that is, nature has never had synthetic protein, having a very attractive application prospects. Synthetic protein method is: to genetic transform bacteria to make its DNA control produce a specific amino acid sequence and then synthesize proteins. It is important to be able to produce and study synthetic proteins at the atomic level for the development of new areas of basic research and for practical applications in more areas.

At the beginning of the design process, supposing a new protein structure that resolves a particular problem or implements a function, and then in turn determines a candidate amino acid sequence that can be folded into such a structure. The Roseetta protein model design software identifies the most promising candidates: the amino acid sequence that folds the lowest energy state of the target structure. Next, these sequences are transferred from the computer to the laboratory, producing synthetic proteins and testing.

At present, there is no technology comparable to the wonderful function of protein implementation. The infinite possibilities of synthetic proteins allow protein design to greatly expand the ability of protein technology. Flarebio offers high-quality recombinant proteins such as recombinant ITGB5 at competitive prices.

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