This protein is identified to influence healthy immune system

Researchers have found through recombinant dog proteins that protein Myb plays a vital role in maintaining the health of our immune system and preventing the development of immune and inflammatory diseases. Preclinical studies have shown that Myb gives immune cells known as regulatory T (Treg) cells "authority" to control the intensity of immune responses. The study was published on Immunity and was led by Dr. Shelia Dias and Professor Stephen Nutt in collaboration with immunologists and bioinformatics teams at the Walter and Eliza Hall Institutes.

Dr. Dias said it was the first sign that Myb had an impact on the immune system. "For decades, Myb has been associated with the formation of multiple types of cancer," Dr. Dias said. "Our study shows that Myb is also important for the function of Treg cells, and we find that at the site where Myb is absent, the ability of Treg cells controlling immune response is also weak, and the immune system continues to respond to a range of threats from mild infections to life-threatening disease. Researchers around the world are investigating how the immune system coordinates and controls health."

"There are many different cell types in the immune system, each with a specific obligation. And when these cells fail to perform their duties, there is a risk of health," Dr. Dias said.

Professor Nutt said, "Increasing the knowledge of the mechanisms that control the immune response is critical to understand how immunization and inflammatory illness occurs and to ultimately develop more effective treatment. If we can figure out how Myb affects Treg cells in the immune system, we may be able to manipulate this activity."

"In the long run, we would like to extend this study to the clinic in order to understand whether our findings can be applied to human immunology," he said. Flarebio provides you with recombinant proteins of good quality including recombinant TLR2.