2016年10月10日星期一

A protein that plays an important role in the development and progression of cancer

Researchers at the Sylvestre Cancer Research Center in the United States have discovered a protein that plays an important role in the development and progression of cancer through research using recombinant dog proteins, and this protein accumulates in dormant cancer cells and forms amyloid small body. Once this amyloid decomposition, cancer cells will be re-active. The study was published in the journal Developmental Cell.

We know that these amyloid bodies are related to the occurrence and development of Alzheimer's disease and Parkinson's disease, the relation of deposition of starch bodies and cancer is not clear. This study suggests that we can apply the knowledge of neuroscience to cancer so as to obtain a variety of types of cancer treatment.

"We found that these proteins are abundantly present in dormant cancer cell bodies, while the heat shock pathway breaks down the amyloid bodies formed by this protein deposition, which in turn restores dormant cancer cells," the experts said.

The study also found that ribosomal non-coding genes control the formation of amyloid bodies in cancer cells, so we can also take this gene as a target to produce drugs. If we can prevent the decomposition of amyloid in cancer cells, then we may be able to keep the cancer cells dormant indefinitely. In addition, we can also try to find another way for cancer cells to produce such amyloid bodies, thus making the active state of cancer cells to dormant state.

Through this study, we can imagine in the future that we may not have to completely remove the cancer cells. We can just keep it in a dormant state. Experts say that they are confident they can develop a new kind of cancer drugs. These drugs take related genes and pathways as targets, and some related drugs have been put into the market, while other drugs are still in the research process. Flarebio provides good-quality recombinant proteins such as recombinant NRG3 at competitive prices.

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