2016年10月24日星期一

Nanotechnology is expected to be used to treat Alzheimer's disease

Researchers have developed a new treatment that uses tiny droplets of fat to carry drugs into the brain to prevent the development of Alzheimer's disease. This method of treatment for targeting drugs to cancer cells has been successfully applied to memory loss in the first recovery of Alzheimer's disease in mice. The study, led by researchers at the University of Lancaster, was funded by the Alzheimer's Society and published in the journal Nanomedicine Nanotechnology, Biology and Medicine, which has published a lot of studies on recombinant human proteins.

This treatment uses tiny fat droplets known as nano-liposomes which are coated in protein fragments. It can prevent the amyloid from accumulating into plaques even at the condition of low concentrations. Amyloid plaques are toxic clumps of proteins that cause damage to cells in the brain of Alzheimer's patients. Mice that were genetically altered to develop Alzheimer's disease were injected with nano-liposomes for three weeks. Those who received the drug restored their long-term memory and were able to recognize the familiar object after 24 hours. In contrast, placebo-injected mice didn't have memory of the objects seen in previous day.

"The research results of this summer show a new discovery of antibody drugs that target amyloid plaques using the body's immune system," said lead investigator David Allsop. However, if these methods are successful, treatment must be instilled through the IV at the clinic and may have some potentially harmful side effects.

Commenting on the innovative approach to dementia treatment, Dr. Doug Brown, Director of Research and Development for Alzheimer's Disease, said, "There were no new dementia drugs in the last 15 years, and we are at a critical moment in dementia research. Crucially, we will continue to sniff new drugs into the brain approach. Although we look forward to the results of ongoing clinical trials, Alzheimer's Association will continue to finance innovative research to address dementia.

Nanotechnology is expected to bring enormous benefits to many people with different types of cancer. It is exciting that it can provide the same hope for the most common forms of dementia one day. Flarebio provides good-quality recombinant proteins like recombinant CDH11.

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