Researchers from Tsinghua University find that Hsp90α can detect liver cancer

Tsinghua University held a press conference on the 19th, saying that the Luo Yongzhang team confirmed that the tumor marker of heat shock protein 90α (Hsp90α) can be used for liver cancer patients using recombinant human proteins in the world for the first time, and the kit has been approved in clinical by the State Food and Drug Administration.

At present, most of the liver cancer patients have been found in middle and advanced stage. Then it is difficult to treat, and the survival is generally poor. The most commonly-used marker for liver cancer is alpha fetoprotein (AFP), but the sensitivity is only about 50%. Luo Yongzhang said that the new liver cancer marker Hsp90a breaks through the limitations of AFP and has a high sensitivity to hepatocellular carcinoma, intrahepatic cholangiocarcinoma, mixed liver cancer and other common types of liver cancer, having great significance for the comprehensive improvement of liver cancer prevention and treatment and reducing liver cancer mortality.

According to Luo Yongzhang team's findings, in patients with negative HCC the AFP test results, the detection rate of Hsp90α is 94%, which proves that Hsp90α is the world's most superior performance of liver cancer markers.

According to reports, the kit not only can detect lung cancer but also can detect liver cancer. As early as 2013, Luo Yongzhang team proved that plasma Hsp90α is a new tumor markers through clinical trials of lung cancer in the world for the first time, and it has been widely used in medical institutions.

Heat shock protein is a kind of protein with molecular chaperone function in cell. Hsp90α is an important member of the heat shock protein family. It is widely distributed in the cells from microbes to mammals and plays an important role in maintaining cell homeostasis. The research results will significantly improve the early detection level of liver cancer and save people from the fear of liver cancer and have a global impact. Flarebio offers good-quality recombinant proteins such as recombinant CDH15 at competitive prices.