2016年5月24日星期二

Intestinal bacteria can also be passed on to next generation

According to Genome-Wide Association Study of more than 1000 pairs of British twins, some parts of the human intestinal bacteria are genetic and can be shaped - microbe is not passed on to their children from their parents, but by the effect of gene. Recently, a study published in the journal Cell - Host and Microorganism, these conclusions provide new cases of species inheriting the bacterial and dietary preferences which are related to dietary favor, metabolism and immune system.

"We plan to identify human genes involved in intestinal flora." Senior author of the study, associate professor Ruth Ley at Cornell University said, "We have identified more than 12 health-related microorganisms that can be inherited. These organisms have environments availability, but they also have some genetic influence."

The researchers analyzed the intestinal bacteria 1126 pairs of twins. This is part of "British twins" project, which took several years of research involving 12,000 twins, to study a large number of diseases. Monozygotic and dizygotic twins grew up with relevant data from, to identify environmental and genetic double impact.

The researchers analyzed the genes of these twins, finding that each participant had 1.3 million small genetic variations (single nucleotide polymorphisms). The research team used whole genome association method to find a group of twin’s link genetic variation and certain bacteria types.

"For genome-wide association study, the sample size of the study is still small, but it also helps to confirm some findings in our small study." Ley said. The study also confirmed several other bacteria can also be found in previous genetic, but the specific genes associated with not found. "Such research raises many questions, but did not give many answers, but it gives us a lot of research ideas." Ley said.

Prior studies have shown that, some natural factors, once thought to play a key role such as caesarean section, natural childbirth, breastfeeding or body mass index, are not as important as previously thought. On the contrary, drugs including heartburn, antibiotics and statins, including drugs, and respiratory frequency, stool hardness and age, are all associated with the presence of intestinal microflora.

More details: http://www.cusabio.com/Recombinant-Protein/Recombinant-Homo-sapiens-Human-Protein-CYR61--11106405.html

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