Japanese study uncovers new mechanisms of AIDS virus infection

Recently published Japanese RIKEN communique said, the researchers found that the new mechanism between HIV infected cells, and found that a compound can contain the infection. This is expected to promote the development of new drugs to treat AIDS.

Previously, the researchers found that the AIDS virus membrane will form tiny pipe is called "tunneling nanotubes", making possible the rapid intercellular material exchange, the virus can be transmitted in this process, but has been unable to ascertain "tunneling nano tube "mechanism.

RIKEN research team let HIV-infected macrophages derived from human blood, it was found macrophages began to form "tunneling nanotubes." But if the lack of Nef protein of HIV infection of macrophages, the observed "tunneling nanotubes" formation, visible Nef protein for "tunneling nanotubes" formation is essential.

In addition, the team also found that if you add a compound called "NPD3064" to macrophages, can impede "tunneling nanotubes" formation. The researchers plan to synthesize similar compounds to curb HIV infection. The study was published in the online edition US Journal of Immunology.

More can be found here: http://www.cusabio.com/ELISA-Kit/Rabbit-creatine-kinase-BB-isoenzyme-CK-BB-ELISA-kit-1035550.html