2015年11月2日星期一
Sleep deficiency may restrain cell growth and brain activity
Everyone knows that sleep is important for our body and health. If adequate sleep can't be ensured, it may not just make you feel tired. A study published by a research team from the University of Tennessee, Knoxville shows that sleep deficiency can short-circuit body system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity.
Albrecht von Arnim is a molecular biologist based in the Department of Biochemistry and Cellular and Molecular Biology. He studied plants for many years and thought that the concepts might well translate to humans.
Protein synthesis is a process that determines how organisms grow and how cells renew themselves. Von Arnim and his team examined how the process changes over the course of the daily day-night cycle. They also explored whether there are such changes are controlled by the organism's circadian clock. Proteins are newly created in each cell by translating messages made from the cell's own DNA, the genome.
The study states that protein synthesis activity changed over the course of the day, and that it was under the influence of the circadian clock.
To be more specific, when our behavior is not coincident with circadian clock, such as jet lag or working at all night, we would both disrupt normal physiological processes and interfere with a more fundamental cellular process, protein synthesis.
Proteins perform the function of muscle action, brain activity, growth and development. For instance, when cells are stressed from a virus infection, they would drastically reduce their protein synthesis activity.
Von Arnim published their findings in the journal Plant Cell.
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