2015年11月12日星期四
The importance of the research on C-reactive protein
As we know that C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is a typical acute phase protein of inflammation. The concentration of CRP can raise more than 1,000 times in the acute condition. CRP is mainly expressed in hepatic cells and secreted to the plasma.
At present, CRP can be used as a nonspecific marker of inflammation in clinical test. It was proved to be a predictor of athereosclerosis these years. The basal level concentration of CRP in plasma is related to the risk of atherogenesis. However, the precise function of CRP is not clear so far in inflammationary regulation and atherogenesis. So the current situation of C-reactive protein and the research on it is quite important.
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