2016年3月16日星期三

The promising method of anticancer: Immunotherapy

Among a variety of new cancer treatment methods, the best hope is to use the body's own immune system to seek and destroy cancer cells everywhere.

The concept of "Immunotherapy" had come out for a long time. It originated from an accidental discovery of US surgeon William Corley in the 1890s. Corley noted, after neck cancer patients in a severe skin infection, tumor miraculously disappeared. Corley took decades later, the mixed bacteria injected into the patient's tumor, some patients achieved good results.

Corley was not clear the mechanism of his therapy work, but today we know that this is due to the immune system has a continuous monitoring, defense capability of cancer cells, occurs when the body means that a cancerous tumor defense system ineffective. With cancer who occasionally lucky enough to find tumors shrink and disappear naturally, this may be due to their immune system activation delay to detect the tumor's sake.

With Mercury's death, the exploration of immunotherapy in the early 20th century temporarily stopped. Now, as people understand the depth of the immune system, the immune system to achieve the use of cancer therapy ideas rises again. After all, we have the conventional case can be activated by the immune system to treat infectious disease vaccines. However, unlike influenza and measles vaccines against cancer is needed is "therapeutic vaccine", as it is used to treat existing tumors rather than prevention of diseases, which is one of the important reasons for the treatment of cancer obstacles to vaccine. Nevertheless, we can still use the immune system in terms of specificity and memory to achieve the purpose of specifically destroy cancer cells, and the vaccine remains active for a long time after the injection.

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