2016年4月19日星期二

The level of vitamin K1 is linked with coronary artery disease

According to a study published online on Apirl 8th in Journal of Thrombosis and Haemostasis shows that there is a relation between gene-decided vitamin K1 levels and coronary artery disease as well as myocardial infarction.

From New York, CUNY School of Public Health, C. Mary Schooling evaluates the risk of coronary artery disease or myocardial infarction in accordance with the level of vitamin K1 genetically determined.

She uses CARDIoGRAMplusC4D (64374 patients and 130,681 cases of control) by independent samples diversity of acquired vitamin K1 with coronary artery disease or myocardial infarction in association estimates, in addition to the use of global lipid genetics research group (196,475 cases of participation researchers) to estimate the association between lipids and vitamin K1.

Schooling observed a positive association between vitamin K1 single nucleotide polymorphism and coronary artery disease or myocardial infarction (odds ratio, 1.17 / unit forecast vitamin K1 levels of gene log transformed), but did not find it and non-transformed normal LDL-cholesterol, high-density lipoprotein, and the positive correlation between triglycerides. With a disease or myocardial infarction, coronary artery more relevant now that the only gene rs2108622, which is functionally closely related to the level of vitamin K1 (odds ratio 1.21).

"Vitamin K may lead to coronary artery disease or myocardial infarction, or whether vitamin K and other coagulation substance decided early prevention of these diseases are related, this may be worth considering," Schooling wrote.

More can be found here: http://www.cusabio.com/ELISA-Kit/Human-anti-caudate-nucleus-CN-autoantibody-ELISA-kit-1080385.html

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