Scientists identify that change of DNA can decrease 3 years of human life. Scientists have found that the differences between the two independent DNA regions of human chromosomes may affect the person's life. These two changes, called variant, relatively common in humans. There are more than two thirds of humans would inherit a single copy of a variant from father or mother.
The study found there is a variant of the single-copy might reduce human life expectancy of up to one year, about two-thousandths people inherit two copies of the variant of the research team predict the average person's life may be reduction of 3 years. One variant associated with increased lung cancer risk and a serious respiratory disease associated genes. Another variant occurs in a gene associated with high cholesterol and Alzheimer's disease.
The study also found that the impact of these variants for male and female life expectancy is different. Genes associated with Alzheimer's disease a greater impact on women, and lung disease associated with a greater impact on men variability.
Researchers at the University of Edinburgh, by analyzing more than 152,000 people have the information they found that these people were involved in UK Biobank study, which is a long record of thousands of volunteers, health information projects. The study has been published in Nature Communications and is funded by the Medical Research Council.
Peter Arthur Population Health and Information Sciences Institute of the University of Edinburgh, Dr. Joshi said that although the impact of these big people life mutation on a little surprised, but remember this is only part of the situation, it is very important. The greatest impact on life is our way of life, which we can control.
Jim Wilson from Arthur Population Health and Information Sciences Institute of the University of Edinburgh said the finding is just tip of the iceberg. With the accumulation of this data, we expect more discoveries. What is exciting is that some may be beneficial to health.
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